生体内での病原性抗体の人工シアリレーションは,自己免疫疾患を弱める

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Updated: Feb 16, 2026

Hippocampal Neuronal Cultures to Detect and Study New Pathogenic Antibodies Involved in Autoimmune Encephalitis
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Jose D Pagan1, Maya Kitaoka1, Robert M Anthony1

  • 1Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.

Cell
|December 26, 2017
PubMed
まとめ

研究者は自己反応性抗体 (IgG) を 抗炎症剤に変える酵素を設計しました このグリコエンジニアリングのアプローチは 免疫性炎症を in vivoで成功裏に軽減し 新しい治療戦略を提供しました

キーワード:
抗体自己免疫疾患の治療グライコシレーション炎症血小板シアリック酸

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