,

Alexander D Barrow1, Melissa A Edeling1, Vladimir Trifonov2

  • 1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Cell
|December 26, 2017
PubMed
まとめ

血小板由来成長因子 (PDGF) -DDは腫瘍の成長を促しますが,NKp44による自然キラー細胞の認識は,抗腫瘍免疫反応を誘発します. この相互作用はサイトカインの放出と腫瘍細胞の成長停止につながり,潜在的な治療標的となる.

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