関連する実験動画

Updated: Feb 16, 2026

In vitro Uncoating of HIV-1 Cores
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In vitro Uncoating of HIV-1 Cores

Published on: November 8, 2011

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残留二極結合からの傾き,不中断,モノメリックHIV-1 gp41トランスメブランヘリックス

Sai Chaitanya Chiliveri1, John M Louis1, Rodolfo Ghirlando1

  • 1Laboratory of Chemical Physics and ‡Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , Bethesda, Maryland 20892, United States.

Journal of the American Chemical Society
|December 27, 2017
PubMed
まとめ

HIV-1 gp41トランスメブラン領域 (TM) は以前は安定したトリマーと考えられていた. しかし,新しいNMR残留二極結合 (RDC) と他の実験データは,TMが単体であり,膜内で高度に秩序付けられていることを明らかにしています.

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