関連する実験動画

Updated: Feb 10, 2026

Telomerase Activity in the Various Regions of Mouse Brain: Non-Radioactive Telomerase Repeat Amplification Protocol TRAP Assay
10:14

Telomerase Activity in the Various Regions of Mouse Brain: Non-Radioactive Telomerase Repeat Amplification Protocol TRAP Assay

Published on: September 2, 2014

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テロメラーゼによる逆転複製フォークの安定化がテロメラー大災害を誘発する

Pol Margalef1, Panagiotis Kotsantis1, Valerie Borel1

  • 1The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.

Cell
|January 2, 2018
PubMed
まとめ

RTEL1欠乏細胞のテロメア破滅は,テロメラーゼが逆転複製フォークに結合することから生じる. テロメラーゼの徴集やフォークの逆転を阻害すると,テロメアの機能障害を防ぐことができます.

キーワード:
ホイエラール・ヒレイダーソン症候群PARP1 についてRECQ1 についてRTEL1 についてZRANB3 についてゲノム安定性について複製フォークの逆転テロメラーゼテロメア

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