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Updated: Feb 16, 2026

Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction
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外螺旋抗体NDT9513727に結合する補完体C5a受容体の構造

Nathan Robertson1, Mathieu Rappas1, Andrew S Doré1

  • 1Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK.

Nature
|January 5, 2018
PubMed
まとめ

C5aアナフィラトキシン化学反応受容体1 (C5aR1) を標的とする小分子は,新たな治療的可能性を秘めています. 構造分析により,NDT9513727は受容体外で結合していることが判明した.

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