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Updated: Feb 16, 2026

Invasive Behavior of Human Breast Cancer Cells in Embryonic Zebrafish
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トポグラフィック・シングル・セル・シーケンシングによって特定された乳がんにおける多細胞侵入

Anna K Casasent1, Aislyn Schalck1, Ruli Gao2

  • 1Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Cell
|January 9, 2018
PubMed
まとめ

トポグラフィック・シングル・セル・シーケンシング (TSCS) は,乳がんが侵襲性になる前に,どのように早期に進化するのかを明らかにします. ほとんどのゲノム変化は 侵入前にダクト内で発生し,マルチクローン侵入モデルをサポートします.

キーワード:
乳がん乳がんの進行ガンゲノミクスクロンの進化コピーナンバーの進化ドクターカルシノーマ in situゲノムの進化腫瘍内異質性侵入するシングルセルシーケンシング

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