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Updated: Feb 15, 2026

DNA Vector-based RNA Interference to Study Gene Function in Cancer
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癌におけるFGFR3-TACC3遺伝子融合の代謝機能

Véronique Frattini1, Stefano M Pagnotta1,2, Tala1

  • 1Institute for Cancer Genetics, Columbia University Medical Center, New York, New York 10032, USA.

Nature
|January 12, 2018
PubMed
まとめ

FGFR3-TACC3 (F3-T3) 遺伝子の融合はミトコンドリア呼吸を活性化することによって癌を誘発する. この代謝経路をターゲットにすることで,F3-T3陽性腫瘍に対する新しい治療戦略が提供されます.

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