関連する実験動画

Updated: Feb 15, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
06:32

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

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結核に対する保護的な先天的免疫を生み出すために,BCGは血液形成幹細胞を教育する

Eva Kaufmann1, Joaquin Sanz2, Jonathan L Dunn1

  • 1Meakins-Christie Laboratories, Department of Medicine, Department of Microbiology and Immunology, Department of Pathology, McGill International TB Centre, McGill University Health Centre, Montreal, QC H4A 3J1, Canada.

Cell
|January 13, 2018
PubMed
まとめ

生まれながらの免疫記憶は,以前は不可能と考えられていたが,バチルス・カルメッテ・ゲーリン (BCG) の培養による血液形成性幹細胞 (HSC) によって生成される. この再プログラムにより 結核に対するマクロファージの保護が強化されます

キーワード:
BCG についてエピジェネティック・リプログラミングマクロファージミコバクテリア 結核幹細胞訓練された免疫

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