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Updated: Jan 17, 2026

Promoting 3-D Aggregation of FACS Purified Thymic Epithelial Cells with EAK 16-II/EAKIIH6 Self-assembling Hydrogel
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Promoting 3-D Aggregation of FACS Purified Thymic Epithelial Cells with EAK 16-II/EAKIIH6 Self-assembling Hydrogel

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α-Klothoは,FGF23ホルモンシグナル伝達のための非酵素分子基架である

Gaozhi Chen1,2, Yang Liu2, Regina Goetz2

  • 1Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.

Nature
|January 18, 2018
PubMed
まとめ

老化を抑制するアルファクロトは,酵素ではなく,骨組みタンパク質として働き,FGF23とFGF23を結合してFGF23のシグナル伝達を促進します. この相互作用はミネラルイオンとビタミンDのホメオスタシスに不可欠です.

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