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Updated: Feb 15, 2026

From Constructs to Crystals – Towards Structure Determination of β-barrel Outer Membrane Proteins
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ミトコンドリア β バレルゲートを通して膜タンパク質の挿入

Alexandra I C Höhr1,2, Caroline Lindau1,2, Christophe Wirth1

  • 1Institute of Biochemistry and Molecular Biology, Centre for Biochemistry and Molecular Cell Research (ZBMZ), Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.

Science (New York, N.Y.)
|January 20, 2018
PubMed
まとめ

ミトコンドリアのOmp85 (外膜タンパク質85) は,前駆体ベータバレルタンパク質を膜に挿入する. この研究は,前駆体がOmp85チャネル内側を通り,横のゲートを通って出ていくことを明らかにしています.

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