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KRAS変異がんを対象に,G12C特異的共性阻害剤を使用する

Matthew R Janes1, Jingchuan Zhang1, Lian-Sheng Li1

  • 1Wellspring Biosciences, San Diego, CA, USA.

Cell
|January 27, 2018
PubMed
まとめ

新しい薬であるARS-1620は,KRAS G12C変異を vivoで効果的に標的にし,がん治療の有望性を示しています. この共性阻害剤は,持続的な標的占有率と腫瘍回帰を達成し,KRAS G12Cを薬剤可能な標的として検証します.

キーワード:
3DカルチャーARS-1620 についてG12C についてKRAS についてNSCLC についてRAS について依存症依存症腫瘍遺伝子

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