人体細胞におけるカンナビノイド CB2受容体発現とリガンドの関与の評価を可能にする選択的フォトアフィニティプロブ

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Updated: Feb 14, 2026

Fluorescence Biomembrane Force Probe: Concurrent Quantitation of Receptor-ligand Kinetics and Binding-induced Intracellular Signaling on a Single Cell
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Fluorescence Biomembrane Force Probe: Concurrent Quantitation of Receptor-ligand Kinetics and Binding-induced Intracellular Signaling on a Single Cell

Published on: August 4, 2015

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Marjolein Soethoudt, Sara C Stolze, Matthias V Westphal1

  • 1Laboratorium für Organische Chemie , Eidgenössische Technische Hochschule Zürich , Vladimir-Prelog-Weg 3 , Zürich 8093 , Switzerland.

Journal of the American Chemical Society
|February 9, 2018
PubMed
まとめ

研究者は2型カンナビノイド受容体 (CB2R) のための新しい光反応性探査機LEI121を開発しました. このツールは,ヒトの免疫細胞における CB2Rの標的の関与の研究と視覚化を可能にし,薬物発見を支援します.

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