環閉による機能的なメタテシス触媒 エネメタテシス: 生きているヘテロテレケリックポリマーのためのワンポットプロトコル
Subhajit Pal1, Fiorella Lucarini1, Albert Ruggi1
1Department of Chemistry , University of Fribourg , Chemin du Musée 9 , CH-1700 Fribourg , Switzerland.
Journal of the American Chemical Society
|February 20, 2018
まとめ
研究者らは,エニネ環閉メタテシスを用いて,新しい機能群を運ぶメタテシス触媒を合成した. これらの触媒は,浄化することなく,生きたヘテロテレケリックポリマーのワンポット合成を可能にします.
科学分野:
- ポリマー化学
- 有機合成
- カタリシス
背景:
- Grubbsの触媒のようなルテニウム (Ru) ベースの触媒は,オレフィン転移で広く使用されています.
- 複雑な分子構造を構築するための経路を提供している.
研究 の 目的:
- 新しい機能群を運ぶメタテシス触媒を合成する.
- 生きたヘテロテレケリックポリマーを合成するためのワンポット方法を開発する.
主な方法:
- Enyneの環閉メタテシスは,商業的なGrubbsの触媒を修正するために使用されました.
- オレフィンの転化に続く環閉転化が,新しい触媒を作るのに用いられた.
- 新しい触媒は,リング開きメタテシスポリメリゼーション (ROMP) によるポリマーの合成に使用された.
主要な成果:
- 商業用ルテニウムベンジリデンの催化剤から,機能群を運ぶメタテシス催化剤を成功して合成した.
- 新しいグラブス型ルテニウムカルベンの触媒を用いて,生きているヘテロテレケリックポリマーの合成を実証した.
- オレフィンと環閉メタテシスの配列を通じて新しい機能的触媒の効率的な合成を達成した.
- ヘテロテレケリックポリマー合成のための様々な機能ベンジリデンおよびアルキリデン誘導体を調査した.
結論:
- エニネの環閉メタテシスは,高度なメタテシス触媒の開発のための効果的な戦略です.
- 開発された触媒は,生きているヘテロテレケリックポリマーの効率的な単体合成を容易にする.
- この研究は,制御されたアーキテクチャを持つ機能的なポリマーを作成するためのツールキットを拡張します.
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