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Updated: Feb 14, 2026

Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans
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Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans

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非典型抗精神病薬リスペリドンに結合するドーパミン受容体の構造

Sheng Wang1, Tao Che1, Anat Levit2

  • 1Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7365, USA.

Nature
|February 22, 2018
PubMed
まとめ

研究者はリスペリドンに結合するドーパミン受容体D2 (DRD2) の結晶構造を発見した. この発見は,より安全な抗精神病薬とパーキンソン病薬の開発に不可欠な新しい薬物結合メカニズムを明らかにしています.

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