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関連する概念動画

Chronic Pharyngitis01:23

Chronic Pharyngitis

12.5K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
12.5K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

750
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
750
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

768
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
768
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

816
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
816
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

383
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
383
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

2.6K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.6K

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関連する実験動画

Updated: Feb 14, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
09:02

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation

Published on: November 26, 2018

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慢性リンパ球白血病

Michael Hallek1, Tait D Shanafelt2, Barbara Eichhorst1

  • 1Department of Internal Medicine, Center of Integrated Oncology Köln Bonn, University Hospital of Cologne, Cologne, Germany.

Lancet (London, England)
|February 26, 2018
PubMed
まとめ

慢性リンパ球性白血病 (CLL) の病原性における最近の進歩は,新しい予後ツールと標的治療法を生み出し,患者の治療結果を改善しました. この見直しでは,進捗状況を報告し,最適な病気管理戦略について議論します.

科学分野:

  • 血液学
  • 腫瘍学
  • 臨床医学

背景:

  • 慢性リンパ球性白血病 (CLL) は,先進国では最も一般的な白血病であり,通常72歳で診断されます.
  • CLLの治療決定は,ライとビネットのステージングシステムと症状の存在によって導かれます.
  • 化学療法と抗CD20モノクローナル抗体は,多くのCLL患者にとって標準的な治療である.

研究 の 目的:

  • CLLの管理における最近の進歩をレビューする.
  • 新しい診断ツールや 標的型治療法を強調する
  • 最適なCLL疾患管理における新たな問題を特定する.

主な方法:

  • 慢性リンパ球性白血病に関する最新の科学文献のレビュー
  • 新しい診断ツールと標的治療法の分析
  • 現在の治療戦略と将来の治療戦略の議論

主要な成果:

  • CLLの病原性を理解する上で 顕著な進歩を遂げました
  • 新しい診断ツールと標的治療法 (イブルチニブ,イデラリシブ,ヴェネトクラックス) の開発
  • 特定のCLL患者のサブセットにおける臨床結果の改善

さらに関連する動画

From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
10:18

From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia

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HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
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HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells

Published on: July 20, 2016

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関連する実験動画

Last Updated: Feb 14, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
09:02

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation

Published on: November 26, 2018

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From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
10:18

From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia

Published on: October 19, 2014

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HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
11:29

HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells

Published on: July 20, 2016

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結論:

  • 標的治療は,ある種のCLL患者の治療基準を変えた.
  • 継続的な研究は 病気の最適な管理を 精進するために不可欠です
  • CLLの治療における新たな問題に対処するために,さらなる調査が必要である.