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Updated: Feb 13, 2026

Single-Molecule Real-Time Visualization of DNA Unwinding by CMG Helicase
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Single-Molecule Real-Time Visualization of DNA Unwinding by CMG Helicase

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ユカリオットCMGヘリケース活性化のメカニズム

Max E Douglas1, Ferdos Abid Ali2, Alessandro Costa2

  • 1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.

Nature
|March 1, 2018
PubMed
まとめ

ユカリオットDNA複製の開始には2つの段階があります. 発火因子は,ミニ染色体維持 (MCM) コンプレクスを2つのCdc45-MCM-GINS (CMG) ヘリケーズに活性化させ,正確なDNA複製を保証する.

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