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Updated: Feb 13, 2026

mRNA Interactome Capture from Plant Protoplasts
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SMAD2/3インタラクトームは,TGFβがm6Aメチル化をプラリポテンシーで制御することを明らかにする

Alessandro Bertero1, Stephanie Brown1, Pedro Madrigal1,2

  • 1Wellcome Trust-MRC Cambridge Stem Cell Institute, Anne McLaren Laboratory and Department of Surgery, University of Cambridge, Cambridge CB2 0SZ, UK.

Nature
|March 1, 2018
PubMed
まとめ

変形成長因子β (TGFβ) 信号は,SMAD2/3タンパク質を通じて細胞運命を調節する. この研究では,SMAD2/3がm6Aメチルトランスフェラーゼ複合体と相互作用し,RNAの安定性と細胞の分化に影響を与えることを明らかにした.

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