ダイナミックなオリゴウレア折りたたみにおける競合する水素結合の極性:分子スプリングのトルションバランス

Romina Wechsel¹, Matej Žabka¹, John W Ward¹

¹School of Chemistry , University of Bristol , Cantock's Close , Bristol BS8 1TS , United Kingdom.

Journal of the American Chemical Society

|March 2, 2018

まとめ

オリゴウレア折り合いは,端末群の水素結合に基づく2つのコンフォマー間で動的に切り替わります. アニオンのゲストは構造的なスイッチを誘発し折りたたみ物質を分子トルションバランスとして示します

科学分野:

超分子化学
有機化学
ポリマー科学

背景:

ポリマーを模倣する合成オリゴーマーです
折りたたみの形状を制御することは機能的な分子を設計するのに不可欠です

研究の目的:

調節可能な端末グループを持つ対称なオリゴウレア・フォルダマーを合成する.
これらの折りたたみの構造的行動とゲスト結合の性質を調査する.

主な方法:

メソサイクロヘキサン-1,2-ダイアミンを用いたオリゴウレア・フォルダマー合成
折りたたみ形状の特徴は,スペクトロスコーピック技術を使用しています.
溶液中の折りたたみ-ゲストの相互作用の研究.

主要な成果:

折りたたみ器は2つのスクルーセンスのコンフォーマーの動的均衡に存在する.
端末群の水素結合能力は,形状の好みを決定する.
アニオン客は,分子内の水素結合ネットワークを再編成することによって,構成的なスイッチを誘導する.

結論:

オリゴウレア・フォルダマーが分子トルションバランスとして作用する.
彼らの形状的好みは,競合する水素結合のペアリングによって支配されます.
特定の分子認識イベントのために設計することができます.

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