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Updated: Feb 13, 2026

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オートゴーナルIL-2サイトカイン受容体複合体を用いて設計されたT細胞の選択的標的化

Jonathan T Sockolosky1,2, Eleonora Trotta3, Giulia Parisi4

  • 1Departments of Molecular and Cellular Physiology and Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|March 3, 2018
PubMed
まとめ

エンジニアリングされたインタールイキン-2 (IL-2) 変種は,選択的にエンジニアリングされたT細胞を標的とし,毒性が低下したがん治療における機能を強化します. このアプローチは,採用細胞免疫療法の有効性を改善する見込みを示しています.

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