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Updated: Feb 13, 2026

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
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Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

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進化したCas9変種,広範囲のPAM互換性と高いDNA特異性

Johnny H Hu1,2,3, Shannon M Miller1,2,3, Maarten H Geurts1,2,3

  • 1Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.

Nature
|March 8, 2018
PubMed
まとめ

科学者たちは,より広い範囲のDNA配列を認識する拡張されたCRISPR-Cas9変種 (xCas9) を開発しました. この突破はヒト細胞のゲノム編集能力と特異性を高めています

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