運動療法とがんにおける心血管毒性
Jessica M Scott1, Tormod S Nilsen2, Dipti Gupta3
1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY (J.M.S., D.G., L.W.H.). scottj1@mskcc.org.
Circulation
|March 14, 2018
まとめ
運動は,がん治療による心毒性を経験するがん患者の心血管の健康を維持するのに役立ちます. この見直しでは,
科学分野:
- 心臓腫瘍学
- 心血管疾患
- 運動生理学
背景:
- がん治療は心臓機能障害 (心臓毒性) を引き起こし,心臓血管系全体に影響を及ぼします.
- この毒性は心不全と冠動脈疾患を引き起こす可能性があります.
- 心血管の準備力を高める戦略は 極めて重要です
研究 の 目的:
- 成人がん患者の心臓毒性の管理のための運動介入の有効性と耐性を検討する.
- パーソナライズされた運動の処方箋のための研究枠組みを提案する.
主な方法:
- 心臓に毒性のあるがん患者の運動介入に関する文献レビュー
- 心血管の準備力に対する運動の影響に関する既存のデータの分析
- パーソナライズされたリスク評価のための概念的枠組みの開発
主要な成果:
- 運動訓練は,がんでない人群で心血管の準備力を高めるための認められた方法です.
- 癌患者の心血管の毒性を軽減する可能性があるという証拠があります.
- 適した運動戦略については さらに研究が必要です
結論:
- 運動による介入は 癌治療による心血管の毒性の予防や管理に 有望です
- パーソナライズされた運動の処方箋は 結果を最適化するための鍵です
- 将来の研究を導くための研究枠組みが提案されています.
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