関連する実験動画

Updated: Nov 20, 2025

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
10:34

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells

Published on: December 9, 2022

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高解像度SHAPE探査によって明らかになったmRNA構造の浸透性規制機能

Anthony M Mustoe1, Steven Busan1, Greggory M Rice2

  • 1Department of Chemistry, University of North Carolina, Chapel Hill, NC, USA.

Cell
|March 20, 2018
PubMed
まとめ

メッセンジャーRNA (mRNA) 構造は遺伝子発現を制御する. この研究は,E. coliにおける多様なmRNA構造を明らかにし,構造が翻訳効率とタンパク質結合に影響することを示しています.

キーワード:
RNA結合タンパク質RNA構造非コーディングRNAリボソームタンパク質翻訳効率翻訳規制トランスレーション カップリング

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Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes11:58

Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes

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RNA Secondary Structure Prediction Using High-throughput SHAPE13:42

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