関連する実験動画

Updated: Feb 13, 2026

Global Identification of Co-Translational Interaction Networks by Selective Ribosome Profiling
06:58

Global Identification of Co-Translational Interaction Networks by Selective Ribosome Profiling

Published on: October 7, 2021

3.0K

リボソームレベルは,ヒトの血液形成における翻訳と血統結合を選択的に調節する

Rajiv K Khajuria1, Mathias Munschauer2, Jacob C Ulirsch3

  • 1Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Berlin-Brandenburg School for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin 13353, Germany.

Cell
|March 20, 2018
PubMed
まとめ

ダイヤモンド - ブラックファン 貧血 (DBA) は,リボソーム 濃度 の 低下 で は なく,血球 の 形成 を 損なう こと を 示し て い ます. この発見は,血液形成幹細胞および前身細胞 (HSPC) の正常および破壊された赤血球系統のコミットメントの重要なレギュレータとしてリボソームレベルを強調しています.

キーワード:
ダイヤモンド・ブラックファン貧血GATA1 についてエリトロポエシス遺伝子についてヘマトポエシス血統の約束リボソーム翻訳

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関連する概念動画

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Translation01:31

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Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
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Termination of Translation01:44

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