関連する実験動画

Updated: Feb 12, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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IRF8はNLRC4炎症体活性化のためのNAIPの転写を調節する

Rajendra Karki1, Ein Lee2, David Place1

  • 1Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Cell
|March 27, 2018
PubMed
まとめ

インターフェロン調節因子8 (IRF8) は,細菌感染症に対する最適なNLRC4炎症体の活性化に不可欠です. IRF8はNAIPを調節し,サイトカインの産生とピロプトーシスを通して宿主防御を強化する.

キーワード:
バークホルディアICSBP についてIRF8 についてNAIP についてNLR についてNLRC4 についてPU1 についてサルモネラカスパース-1炎症ゾーム

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