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Updated: Feb 12, 2026

Probing High-density Functional Protein Microarrays to Detect Protein-protein Interactions
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タンパク質のクロトニル化のための化学的探査機

Jeffrey Bos1, Tom W Muir1

  • 1Frick Laboratory, Department of Chemistry , Princeton University , Princeton , New Jersey 08544 , United States.

Journal of the American Chemical Society
|March 28, 2018
PubMed
まとめ

研究者らは,重要な表遺伝子調節体である タンパク質ライシンクロトニレーションを検出する新しい化学的探査機を開発した. このツールは,クロトニル化がヒストンのアセチル化を強化し,遺伝子転写に影響を与えるポジティブなフィードバックループを明らかにします.

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