関連する実験動画

Updated: Feb 12, 2026

High-throughput Nitrobenzoxadiazole-labeled Cholesterol Efflux Assay
08:18

High-throughput Nitrobenzoxadiazole-labeled Cholesterol Efflux Assay

Published on: January 7, 2019

9.6K

コレステロール流出経路 炎症体活性化,NETosis,およびアテロゲネシスを抑制する

Marit Westerterp1,2, Panagiotis Fotakis1, Mireille Ouimet3,4

  • 1Division of Molecular Medicine (M.W., P.F., A.E.B., M.M.M., W.W., S.A., N.W., C.L.W., A.R.T.).

Circulation
|March 29, 2018
PubMed
まとめ

骨髄細胞におけるコレステロールの蓄積はNLRP3炎症体を活性化し,中性粒子の活性化と動脈硬化性斑塊の形成を促します. この経路はタンジェ病の患者にとって重要であり,コレステロール,炎症,心血管疾患のリスクとの関連を強調しています.

キーワード:
ATP結合用カセットトランスポーター動脈硬化症コレステロール,HDL細胞外トラップインフラマソーム

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