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膀がんの患者由来器官モデルにおける腫瘍の進化と薬剤反応

Suk Hyung Lee1, Wenhuo Hu2, Justin T Matulay3

  • 1Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA; Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA; Department of Urology, Columbia University Medical Center, New York, NY 10032, USA; Department of Systems Biology, Columbia University Medical Center, New York, NY 10032, USA; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA.

Cell
|April 7, 2018
PubMed
まとめ

研究者らは患者から得られた膀がんオーガノイドを開発し 新しいモデルシステムを開発しました これらのオルガノイドは,ヒトの膀腫瘍の多様性と進化を正確に反映し,精密な癌医学研究を支援しています.

キーワード:
膀 がんクロンの進化薬物反応患者からのオーガノイド患者からの異種移植

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