Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Mass Analyzers: Overview01:13

Mass Analyzers: Overview

1.8K
The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
1.8K
Tumor Immunotherapy01:27

Tumor Immunotherapy

2.0K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.0K
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

1.6K
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
1.6K
Tumor Progression02:07

Tumor Progression

7.5K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.5K
The Tumor Microenvironment02:17

The Tumor Microenvironment

7.9K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
7.9K
Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

989
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
989

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles.

Scientific reports·2025
Same author

Three-dimensional genome landscape of primary human cancers.

Nature genetics·2025
Same author

Protocol for obtaining cancer type and subtype predictions using subSCOPE.

STAR protocols·2025
Same author

Protocol for assessing distances in pathway space for classifier feature sets from machine learning methods.

STAR protocols·2025
Same author

Classification of non-TCGA cancer samples to TCGA molecular subtypes using compact feature sets.

Cancer cell·2025
Same author

Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers.

Science (New York, N.Y.)·2024

関連する実験動画

Updated: Feb 12, 2026

Analyzing Tumor Gene Expression Factors with the CorExplorer Web Portal
08:00

Analyzing Tumor Gene Expression Factors with the CorExplorer Web Portal

Published on: October 11, 2019

8.0K

スナップショット:TCGA分析された腫瘍

Amy Blum1, Peggy Wang1, Jean C Zenklusen1

  • 1Center for Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Cell
|April 7, 2018
PubMed
まとめ

癌ゲノムアトラス (TCGA) プログラムは多くの腫瘍のタイプを特徴づけています. この概要は,TCGAマーカーペーパーから各がんの主要な発見を強調しています.

科学分野:

  • 腫瘍学
  • ゲノミクス
  • 癌 研究

背景:

  • 癌ゲノムアトラス (TCGA) プログラムは,様々な癌の総合的なゲノムデータを生成しています.
  • 腫瘍の分子構造を理解することは 癌の診断と治療の進歩に不可欠です

研究 の 目的:

  • TCGAプログラムで分析された腫瘍の統合リストを提供するためです.
  • 特徴づけられた腫瘍のタイプごとに 最も重要なゲノム発見を要約します

主な方法:

  • TCGAのマーカー・ペーパーのレビュー
  • 腫瘍ゲノム学に関する重要な発見の特定

主要な成果:

  • TCGAで特徴づけられた腫瘍の総合的なカタログ.
  • 主要な発見の要約,ドライバー変異,ゲノム変異,各腫瘍の分子サブタイプを含む.

結論:

  • TCGAプログラムは ゲノムレベルで 癌の理解を大幅に進めてきました
  • この資料は 癌の研究者や臨床医にとって 重要な参考資料となります

さらに関連する動画

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody
07:36

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody

Published on: May 16, 2020

5.9K
Establishment of a Co-culture System of Patient-Derived Colorectal Tumor Organoids and Tumor-Infiltrating Lymphocytes (TILs)
08:42

Establishment of a Co-culture System of Patient-Derived Colorectal Tumor Organoids and Tumor-Infiltrating Lymphocytes (TILs)

Published on: June 27, 2025

2.3K

関連する実験動画

Last Updated: Feb 12, 2026

Analyzing Tumor Gene Expression Factors with the CorExplorer Web Portal
08:00

Analyzing Tumor Gene Expression Factors with the CorExplorer Web Portal

Published on: October 11, 2019

8.0K
Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody
07:36

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody

Published on: May 16, 2020

5.9K
Establishment of a Co-culture System of Patient-Derived Colorectal Tumor Organoids and Tumor-Infiltrating Lymphocytes (TILs)
08:42

Establishment of a Co-culture System of Patient-Derived Colorectal Tumor Organoids and Tumor-Infiltrating Lymphocytes (TILs)

Published on: June 27, 2025

2.3K