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Vms1およびANKZF1ペプチジル-tRNAヒドロレーゼは,停止したリボソームから新生鎖を放出する

Rati Verma1,2,3, Kurt M Reichermeier2,4, A Maxwell Burroughs5

  • 1Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA, USA.

Nature
|April 11, 2018
PubMed
まとめ

研究者らはVms1をペプチジル-tRNAヒドローラーゼとして特定し,停滞したリボソームタンパク質の分解に不可欠である. この発見は タンパク質毒性ストレスと 神経変異を予防する リボソーム品質管理の重要なステップを 明らかにしています

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