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Updated: Feb 12, 2026

In Vivo Targeting of Neural Progenitor Cells in Ferret Neocortex by In Utero Electroporation
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ASPM ノックアウトフレットは,脳皮質の大きさを制御する進化的メカニズムを明らかにします

Matthew B Johnson1,2, Xingshen Sun3,4,5, Andrew Kodani1,2

  • 1Division of Genetics and Genomics, Manton Center for Orphan Disease Research, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Nature
|April 13, 2018
PubMed
まとめ

フレットにおける異常なスパインドル型小頭症関連 (ASPM) 遺伝子喪失は小頭症を引き起こし,神経原始細胞の行動を制御することによって人間の脳サイズと折り畳みを調節する役割を明らかにします.

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