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Updated: Feb 12, 2026

Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
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CaV1. 2 - ガレクチン-1 タンパク質の相互作用を標的とした血圧の調節

Zhenyu Hu1, Guang Li2, Jiong-Wei Wang1,3,4

  • 1Department of Physiology, Yong Loo Lin School of Medicine (Z.Y.H., J.-W.W., D.Y., M.C.L., Y.P.W., T.W.S.), National University of Singapore.

Circulation
|April 14, 2018
PubMed
まとめ

ガレクチン-1 (Gal-1) は,CaVβ結合を妨害し,血圧に影響することで,L型CaV1.2チャネルのタンパク質分解を促進する. この相互作用をターゲットにすることが,高血圧の潜在的治療戦略を提供します.

キーワード:
血圧カルシウムチャネル,L型ガレクチン-1高血圧プロテアソーム・エンドペプチダゼ複合体

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