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Updated: Feb 11, 2026

miRNA Expression Analyses in Prostate Cancer Clinical Tissues
11:29

miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

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CTLA-4封鎖に対する臨床的結果を差別するがん-生殖線抗原発現

Sachet A Shukla1, Pavan Bachireddy2, Bastian Schilling3

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Broad Institute, Cambridge, MA 02142, USA.

Cell
|April 17, 2018
PubMed
まとめ

特定のMAGE- A遺伝子シグネチャは,メラノーマにおけるCTLA- 4阻害に対する耐性を予測する. この抵抗は,抑制されたオートファジーと関連しており,オートファジー誘導が潜在的な治療法であることを示唆しています.

キーワード:
CTLA-4 についてマージーAPD-1 についてオートファジー癌の生殖線抗原チェックポイントの封鎖免疫遺伝学免疫療法イピリムマブメラノーマ

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Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood09:29

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