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Updated: Feb 11, 2026

CRISPR/Cas9 Ribonucleoprotein-mediated Precise Gene Editing by Tube Electroporation
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Published on: June 20, 2019

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細胞型特異的な遺伝子編集のためのCRISPR-Cas9エンドヌクレアスの受容体媒介配送

Romain Rouet, Benjamin A Thuma1, Marc D Roy2

  • 1Pfizer Medicine Design , Groton , Connecticut 06340 , United States.

Journal of the American Chemical Society
|April 19, 2018
PubMed
まとめ

研究者はCRISPR-Cas9遺伝子編集タンパク質を 特定の細胞を標的とするリガンドで設計した. この受容体媒介による配送は,肝細胞の精密な遺伝子編集を 厳しい方法なしに可能にし, in vivo 応用への道を開きます.

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