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Updated: Feb 11, 2026

An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions
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ニューロペプチドY1受容体におけるリガンド結合モードの構造的基礎

Zhenlin Yang1,2, Shuo Han1,3, Max Keller4

  • 1Chinese Academy of Sciences Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

Nature
|April 20, 2018
PubMed
まとめ

研究者は,神経ペプチドY (NPY) Y1受容体の結晶構造を決定した. これはNPY受容体アンタゴニストとアゴニストが結合する方法を明らかにし,肥満と癌に対する薬剤の発見を助けます.

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