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関連する概念動画

Novel and Innovative Hybrid Technique for Type A Aortic Dissection06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

847
The protocol describes ascending aortic replacement combined with endovascular coverage of the entire aortic arch with a fenestrated stent graft in a patient with acute type A aortic dissection in the absence of a tear in the aortic...
847
Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft05:25

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft

1.2K
This study presents a surgical porcine model of chronic myocardial ischemia due to progressive coronary artery stenosis, resulting in impaired cardiac function without infarction. Following ischemia, animals undergo off-pump coronary artery bypass graft with epicardial placement of stem cells-derived exosomes-laden collagen patch. This adjunctive therapy improves myocardial function and...
1.2K
Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

2.5K
This protocol describes the steps for the creation of a rabbit model with two elastase-digested aneurysms with different hemodynamics (stump and bifurcation constellation). This allows the testing of novel endovascular devices in aneurysms with different angioarchitecture and hemodynamic conditions within a single animal.
2.5K
A Chronic Cardiac Ischemia Model in Swine Using an Ameroid Constrictor08:22

A Chronic Cardiac Ischemia Model in Swine Using an Ameroid Constrictor

11.1K
The purpose of this protocol is to demonstrate the placement of a delayed constricting device (an ameroid constrictor) around a coronary artery in a swine model. This device creates an ischemic area of the heart that is useful for studying new diagnostic imaging techniques and new methods of treatment.
11.1K
Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

19.1K
Surgical correction of ALCAPA is highly recommended, regardless of age or the degree of intercoronary collateralization. This protocol presents a technique for the direct re-implantation of adult-type ALCAPA into the aorta to re-establish the dual-coronary perfusion. Whenever feasible, direct re-implantation is preferred to other surgical correction...
19.1K
A New Murine Model of Endovascular Aortic Aneurysm Repair08:51

A New Murine Model of Endovascular Aortic Aneurysm Repair

14.7K
Histological and biochemical modifications after aneurysm endograft exclusion are still unclear. We describe a new model of endograft implantation on a murine aneurysm. Through thrombus analysis with and without persistant circulating blood stream interface, and new endovascular biomaterials evaluation, this model will help to better understand endovascular aneurysm exclusion...
14.7K

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関連する実験動画

Updated: Jan 20, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization
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Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

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マウス の 早期 発達 に 注意 を 引く

Tristan Frum1, Amy Ralston1

  • 1Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA.

Cell
|April 21, 2018
PubMed
まとめ

動的アクチン運動はマウス胚の表皮形成の鍵であり,哺乳類の発達中に細胞の運命をどのように形成するかについての新しい洞察を明らかにしています.

科学分野:

  • 発達生物学
  • 細胞生物学
  • 胚科

背景:

  • エピテリア化は胚の発達に不可欠です
  • 細胞メカニズムを理解することは 肝心なことです
  • この過程におけるダイナミック・アクチンの役割は,これまでの研究で完全に解明されていない.

研究 の 目的:

  • アクチン細胞骨格のダイナミックな再配置が表皮化における役割を調査する.
  • このアクチンダイナミクスがマウスの胚形成過程で細胞運命を決定する仕組みを調査する.

主な方法:

  • タイムラップ画像技術を使いました
  • 生きたマウスの胚の細胞の振る舞いを観察した.
  • 細胞と亜細胞レベルでアクチンダイナミクスを分析した.

主要な成果:

  • 動的アクチン運動が表皮化プロセスに不可欠であることを示した.
  • アクチンポリメリゼーションとデポリメリゼーションの特定パターン.
  • 細胞の形状の変化と組織形成と相関するアクチンダイナミクス

結論:

さらに関連する動画

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

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Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

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関連する実験動画

Last Updated: Jan 20, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization
05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

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Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
07:04

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit

Published on: April 15, 2021

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Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

19.1K
  • ダイナミックなアクチン再編成は哺乳類の胚膜形成の根本的なメカニズムである.
  • この研究は,細胞の運命の出現に関する新しい視点を提供します.
  • 発見は発達過程の研究に新しい道を開く.