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Updated: Feb 11, 2026

In vitro Methylation Assay to Study Protein Arginine Methylation
10:01

In vitro Methylation Assay to Study Protein Arginine Methylation

Published on: October 5, 2014

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FUS相分離は,分子チャペロンとアルギニンカチオン-π相互作用のメチル化によって調節される

Seema Qamar1, GuoZhen Wang1, Suzanne J Randle1

  • 1Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK.

Cell
|April 21, 2018
PubMed
まとめ

アルギニンの低メチル化によるFUSタンパク質の凝縮は,前頭葉変性 (FTLD) を引き起こします. FUSの凝結を防ぎ ニューロンの機能を救います

キーワード:
AFM-IRアルギニンメチル化カチオン-πシトルリン化フロントテンポラル認知症膜のない器官ニューロンのリボ核タンパク質の粒フェーズ分離段階感度の高い光染料新しいシナプスタンパク質の合成

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