Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

9.3K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
9.3K
Export of Mitochondrial and Chloroplast Genes02:19

Export of Mitochondrial and Chloroplast Genes

4.2K
A eukaryotic cell can have up to three different types of genetic systems: nuclear, mitochondrial, and chloroplast. During evolution, organelles have exported many genes to the nucleus; this transfer is still ongoing in some plant species. Approximately 18% of the Arabidopsis thaliana nuclear genome is thought to be derived from the chloroplast’s cyanobacterial ancestor, and around 75% of the yeast genome derived from the mitochondria’s bacterial ancestor. This export has occurred...
4.2K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

17.0K
The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
17.0K
The Inner Mitochondrial Membrane01:28

The Inner Mitochondrial Membrane

4.8K
The inner mitochondrial membrane is the primary site of ATP synthesis. The inner membrane domain that forms a smooth layer adjacent to the outer membrane is called the inner boundary membrane. This domain contains membrane transporters that drive metabolites in and out of the mitochondria.  In contrast, the inner membrane network that invaginates into the matrix space is called the cristae membrane. This domain accounts for principle mitochondrial function as it accommodates the protein...
4.8K
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

15.0K
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
15.0K
Mitochondrial Membranes01:45

Mitochondrial Membranes

17.2K
A single mitochondrion is a bean-shaped organelle enclosed by a double-membrane system. The outer membrane of mitochondria is smooth and contains many porins - the integral membrane transporters. Porins enable free diffusion of ions and small uncharged molecules through the outer mitochondrial membrane but limit the transport of molecules larger than 5000 Daltons. Further, the outer mitochondrial membrane forms a unique structure called membrane contact sites with other subcellular organelles,...
17.2K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Uncovering syntrophic potential from genome-resolved metagenomics of suspended and granular anaerobic digestion sludges.

FEMS microbiology ecology·2026
Same author

Prediction of eukaryotic cellular complexity in Asgard archaea using structural modelling.

Nature microbiology·2026
Same author

Diversity, ecology, cell biology and evolution of the Asgard archaea.

Nature reviews. Microbiology·2026
Same author

Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor.

Nature·2026
Same author

EMBO Press co-evolves with molecular ecology and evolutionary biology.

The EMBO journal·2026
Same author

Author Correction: Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes.

Nature·2026

関連する実験動画

Updated: Feb 11, 2026

Author Spotlight: Unveiling Oxidative Phosphorylation System Dynamics and Mitochondrial Roles in Health and Disease
05:45

Author Spotlight: Unveiling Oxidative Phosphorylation System Dynamics and Mitochondrial Roles in Health and Disease

Published on: May 3, 2024

2.1K

採取したアルファプロテオバクテリア以外の深層ミトコンドリア起源

Joran Martijn1, Julian Vosseberg1,2, Lionel Guy3

  • 1Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

Nature
|April 27, 2018
PubMed
まとめ

ミトコンドリアは細胞のエネルギーに不可欠で,以前考えられていたようにリケチアから進化しなかった. 新しいゲノムデータは,彼らの祖先が既知のアルファプロテオバクテリアより先行しており,初期の真核生物の進化を再評価する必要があります.

さらに関連する動画

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
07:24

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing

Published on: February 10, 2023

2.0K
Determination of Mitochondrial Respiration and Glycolysis in Ex Vivo Retinal Tissue Samples
08:45

Determination of Mitochondrial Respiration and Glycolysis in Ex Vivo Retinal Tissue Samples

Published on: August 4, 2021

4.9K

関連する実験動画

Last Updated: Feb 11, 2026

Author Spotlight: Unveiling Oxidative Phosphorylation System Dynamics and Mitochondrial Roles in Health and Disease
05:45

Author Spotlight: Unveiling Oxidative Phosphorylation System Dynamics and Mitochondrial Roles in Health and Disease

Published on: May 3, 2024

2.1K
Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
07:24

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing

Published on: February 10, 2023

2.0K
Determination of Mitochondrial Respiration and Glycolysis in Ex Vivo Retinal Tissue Samples
08:45

Determination of Mitochondrial Respiration and Glycolysis in Ex Vivo Retinal Tissue Samples

Published on: August 4, 2021

4.9K

科学分野:

  • 細胞生物学
  • 進化生物学
  • ゲノミクス

背景:

  • ミトコンドリアは,エンドシンビオシスから生じる重要なATP生成器官である.
  • ミトコンドリアのアルファプロテオバクテリア起源が示唆されている.
  • 以前の研究では,特定のアルファプロテオバクテリアの祖先に関して矛盾する結果が得られた.

研究 の 目的:

  • ミトコンドリアの遺伝子配置を再評価する
  • アルファプロテオバクテリア内のミトコンドリアの最も近い親族を特定する.
  • ミトコンドリアの祖先の進化的起源と性質を明らかにする

主な方法:

  • 海洋メタゲノムデータセットのゲノム解析
  • アルファプロテオバクテリアのゲノムサンプルを12の異なるクラードで増やした.
  • 長い枝の引き寄せと組成のバイアスを扱う系統学的分析.

主要な成果:

  • ミトコンドリアはリケチアスや 既知のアルファプロテオバクテリア系に由来しない.
  • 系統遺伝学的な分析では 試料のアルファプロテオバクテリアより前に 祖先が分岐したことを示している.
  • この研究は,12の異なるアルファプロテオバクテリアのクラードに関する新しいゲノムデータを提供します.

結論:

  • ミトコンドリアの進化的起源は,以前に特定されたアルファプロテオバクテリア群とは異なる.
  • ミトコンドリアの祖先に関する以前の仮説は,新しい発見に基づいて再評価を必要とする.
  • この研究は初期の真核細胞の進化と 臓器細胞の起源の理解を 洗練しています