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Updated: Jan 20, 2026

Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays
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GPCRによるβアレスティンの触媒活性化

Kelsie Eichel1,2, Damien Jullié1,2, Benjamin Barsi-Rhyne1,2

  • 1Department of Cellular and Molecular Pharmacology, University of California, San Francisco School of Medicine, San Francisco, CA, USA.

Nature
|May 4, 2018
PubMed
まとめ

この研究では,ベータアレスティン (β-アレスティン) がGタンパク質結合受容体 (GPCR) によって活性化される新しい方法が明らかになりました. このメカニズムは,安定した構造ではなく,一時的なGPCRコアエンゲージメントで, 異なる細胞信号伝達経路につながります.

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