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Updated: Feb 11, 2026

Preparation of High-Temperature Sample Grids for Cryo-EM
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Published on: July 26, 2021

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クリオ-エム構造によって解明されたヒトSKカルモジュリンチャネル複合体の活性化メカニズム

Chia-Hsueh Lee1, Roderick MacKinnon2

  • 1Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, NY 10065, USA.

Science (New York, N.Y.)
|May 5, 2018
PubMed
まとめ

小伝導性カルシウム活性化カリウム (SK) チャンネルはニューロン機能に不可欠です. 新しい冷凍-EM構造は,カルモジュリン結合がこれらの重要なSKチャネルをどのように開くかを明らかにします.

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