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Updated: Feb 11, 2026

High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis
09:33

High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis

Published on: October 15, 2019

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スプライソームプロファイリングは,ニュクレオチド解像度でダイナミックなRNPの操作を視覚化します

Jordan E Burke1, Adam D Longhurst1, Daria Merkurjev2

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell
|May 5, 2018
PubMed
まとめ

新しいツールは,スプライセソーム結合RNAを in vivo で世界的にプロファイルし,酵母種間のスプライシングの調節と共進化を明らかにします. この定量的な方法は,遺伝子発現におけるこの重要なRNP複合体の理解を進める.

キーワード:
mRNA前スプライシングスプライソームスプライシングカタリシスsplicing fidelity スプライシング フィデリティ

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