DNA修復複合体のダイナミックアーキテクチャとメオティック再結合の場所におけるシナプトネマ複合体

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Updated: Feb 10, 2026

Super-Resolution Microscopy of the Synaptonemal Complex Within the Caenorhabditis elegans Germline
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Super-Resolution Microscopy of the Synaptonemal Complex Within the Caenorhabditis elegans Germline

Published on: September 13, 2022

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Alexander Woglar1, Anne M Villeneuve1

  • 1Departments of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford, CA, USA.

Cell
|May 15, 2018
PubMed
まとめ

ミオティック・ダブル・ストランド・ブレイク (DSB) の修復は,ゲノムの完全性にとって極めて重要です. シナプトネマル複合体 (SC) は,非CO修復を保証しながら,クロスオーバー (CO) を促進して,DSB修復結果を調節する可能性があります.

キーワード:
DNA 修復ミエオシス再組み合わせスーパー解像度シナプトネマル複合体

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