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Updated: Feb 10, 2026

Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c
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ヒトのサイトクロームCYP17A1:17- ハイドロキシプロゲステロンによるライアース活性低下の構造的根拠

Piotr J Mak1, Ruchia Duggal2, Ilia G Denisov2

  • 1Department of Chemistry , Marquette University , Milwaukee , Wisconsin 53233 , United States.

Journal of the American Chemical Society
|May 16, 2018
PubMed
まとめ

アンドロゲン産生におけるサイトクロームP450 (CYP17A1) 酵素の活性性は,プレグネノロンとプロゲステロンの間で異なっている. この研究は,前立腺がんの研究に影響を与える,CYP17A1がプロゲステロンとより低効率である理由を説明し,反応メカニズムを明確にします.

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