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Mxra8は複数の関節性アルファウイルスに対する受容体である

Rong Zhang1, Arthur S Kim1,2, Julie M Fox1

  • 1Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA.

Nature
|May 18, 2018
PubMed
まとめ

研究者らは,Mxra8を,関節性アルファウイルスの侵入における主要な宿主因子として特定した. Mxra8をブロックする抗体や融合タンパク質を標的とした治療は,細胞培養やマウスモデルにおけるウイルス感染と疾患症状を減少させた.

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