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Updated: Feb 10, 2026

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
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Staphylococcus aureusにおける抗生物質感知ヒスティジンキナーゼであるNsaSのトランスメブラン領域の構造と機能

Manasi P Bhate1, Thomas Lemmin1, Georg Kuenze2

  • 1Department of Pharmaceutical Chemistry , UC San Francisco , San Francisco , California 94158 , United States.

Journal of the American Chemical Society
|May 18, 2018
PubMed
まとめ

この研究は,Staphylococcus aureusの重要なヒスティジンキナーゼであるNsaSの構造を明らかにし,そのトランスメブラン領域と柔軟なリンク器を強調しています. これらの特徴は 感染時に抗菌剤と先天的な免疫を感知するのに 極めて重要です

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