相対湿度の変化に反応して電力を発生し,保持し,放電できるタンパク質の自己組み立て
Nathan A Carter1, Tijana Z Grove1
1Department of Chemistry, Macromolecules Innovations Institute, and The Virginia Tech Center for Sustainable Nanotechnology , Virginia Tech 900 West Campus Drive , Blacksburg , Virginia 24061 , United States.
Journal of the American Chemical Society
|May 19, 2018
まとめ
エンジニアリングされた重複タンパク質は 移動幅が大きく 動作が速く 伝導性が高く 新しいセンサーや装置を可能にします 機械的なストレスから電圧を生成する ピエゾのような振る舞いを示しています
科学分野:
- バイオマテリアル科学
- タンパク質工学
- ナノテクノロジー
背景:
- 刺激に反応する材料は 先進的なセンサーや装置にとって不可欠です
- タンパク質ベースの材料は バイオ・インテグレーテッド・エレクトロニクスに ユニークな特性を備えています
- エンジニアリングされたタンパク質は 特定の機械的および電気的機能のために設計できます
研究 の 目的:
- 自分で組み立てた複製タンパク質の動作と電気的性質を調査する.
- 機能的なデバイスのアプリケーションのためのコンセンサステトラトリコペプチドリピートタンパク質 (CTPR18) の可能性を調査する.
- タンパク質の組立,形態,刺激反応の関係を理解する.
主な方法:
- エンジニアリングによる重複タンパク質Consensus Tetratricopeptide Repeat protein (CTPR18) の自己組み立て
- 材料の伝導性と形態学的グラデーションの特徴
- 動作モード (曲げること,曲げること,折りたたむこと) とピエゾのような動作の分析.
主要な成果:
- CTPR18の材料は,大きな移転量,迅速なアクチュエーションを示した.
- 自己組み立てたタンパク質フィルムで高いイオン伝導率 (7.1 × 10−2) を達成した.
- メカニカル入力からの電圧生成を含む,調節可能なアクチュエーションとピエゾのような効果が実証されています.
結論:
- 自己組み立てのCTPR18タンパク質は 特殊なアクチュエーションと電気的性質を備えています
- イオンの性質と調節可能な形態は 刺激に反応する様々な行動を可能にします
- この研究により バイオポリマーベースの高度なセンサーとアクチュエータの開発が進んでいます
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