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Updated: Feb 10, 2026

Investigating Intestinal Inflammation in DSS-induced Model of IBD
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食事と微生物によるオキサゾールは,アリル炭化水素受容体の反応を調節することによって腸炎を引き起こします

Shankar S Iyer1, Thomas Gensollen1, Amit Gandhi1

  • 1Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Cell
|May 19, 2018
PubMed
まとめ

環境に由来するオキサゾールは,T細胞反応を調節することによって,CD1d依存の腸炎を誘発する. アリル炭化水素受容体 (AhR) 経路は,トリプトファンの代謝物を調節することによって炎症を抑制する.

キーワード:
CD1dアリル炭化水素受容体インドレアミン2,3ダイオキシゲナーゼ炎症性腸疾患腸内皮質細胞微生物群マイクロシン粘膜の炎症自然殺しT細胞オクサゾールトリプトファン

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