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Updated: Feb 10, 2026

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神経ペプチド Tac2は,慢性的な社会的孤立ストレスによって引き起こされる分散した脳状態を制御する

Moriel Zelikowsky1, May Hui1, Tomomi Karigo1

  • 1Division of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.

Cell
|May 19, 2018
PubMed
まとめ

慢性的な社会孤立ストレス (SIS) は,タキキニン2 (Tac2) /ニューロキニンB (NkB) を脳全体で向上させることでマウスの行動を変化させます. NkB受容体 (Nk3R) を阻害することで,これらの効果は逆転し,治療の可能性を示唆した.

キーワード:
BNST についてDMH についてNk3R についてNkB についてタック2攻撃性アミグダラ恐怖ニューロペプチド社会的孤立ストレス

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