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Updated: Jul 13, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

EGF受容体の親和性は,細胞内カルシウムとタンパク質キナーゼCによって調節されます

J C Fearn, A C King

    Cell
    |April 1, 1985
    PubMed
    まとめ

    フォルボールのエステルは,タンパク質キナーゼCを活性化することによって,細胞表面受容体への表皮成長因子 (EGF) の結合を阻害する.このカルシウムに依存する過程は,無傷な細胞において極めて重要であり,EGF受容体のリン酸化を含む.

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