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Updated: Feb 9, 2026

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
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ダイナミックアロステリーは,酵素の寒さへの適応を促す

Harry G Saavedra1,2, James O Wrabl1,2, Jeremy A Anderson1,2

  • 1Department of Biology, Johns Hopkins University, Baltimore, MD, USA.

Nature
|June 8, 2018
PubMed
まとめ

生物は酵素の進化的変化によって新しい環境に適応する. この研究は,遠隔の変異が酵素活性にアロステル的に調節し,活性部位の構造を変えることなく,基板の親和性および周回率に影響を与える方法を示しています.

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