関連する実験動画

Updated: Feb 9, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
13:41

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus

Published on: March 8, 2012

13.0K

反同型親和性成熟は,繰り返し発生するエピトープに対するヒトB細胞の反応を改善する

Katharina Imkeller1,2, Stephen W Scally3, Alexandre Bosch3

  • 1B Cell Immunology, German Cancer Research Institute, Heidelberg, Germany.

Science (New York, N.Y.)
|June 9, 2018
PubMed
まとめ

この研究では,マラリア寄生虫の環球胞子タンパク質 (PfCSP) のような反復性抗原が抗体保護を強化する方法を明らかにしました. 同型抗体の相互作用は,B細胞の活性化と抗体の親和性を改善し,病原体の防御を助ける.

さらに関連する動画

Maturation of Human Stem Cell-derived Cardiomyocytes in Biowires Using Electrical Stimulation10:11

Maturation of Human Stem Cell-derived Cardiomyocytes in Biowires Using Electrical Stimulation

Published on: May 6, 2017

9.5K
Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells13:58

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells

Published on: October 22, 2012

18.7K

関連する概念動画

Affinity and Avidity01:41

Affinity and Avidity

Overview
39.2K
Electron Affinity03:07

Electron Affinity

The electron affinity (EA) is the energy change for adding an electron to a gaseous atom to form an anion (negative ion).
43.4K
Maturation of Endosomes01:28

Maturation of Endosomes

The early endosome containing internalized molecules matures through transformations in its location, morphology, intraluminal pH, and membrane protein composition. Together, these changes result in a more acidic late endosome that contains multiple intraluminal vesicles; therefore, the late endosome is also called a multivesicular body (MVB).
Changes in location
The maturing endosome moves along microtubules from the periphery of the cell towards the perinuclear region. This movement of the...
5.9K
Affinity Chromatography01:03

Affinity Chromatography

Affinity chromatography is a powerful technique extensively utilized for separating and purifying specific biomolecules from complex mixtures. It capitalizes on the highly selective binding between an analyte and its counterpart, such as antibody-antigen interactions. The counterpart is immobilized on the stationary phase, forming an affinity column. The stationary phase typically consists of solid support, such as agarose or porous glass beads, immobilizing the affinity ligand. The mobile...
3.1K
Bacterial Protein Maturation01:26

Bacterial Protein Maturation

Bacterial protein maturation is a tightly regulated process that ensures newly synthesized polypeptides achieve correct functional conformations. This maturation involves a series of modifications, folding events, and quality control steps, often assisted by specialized chaperone proteins.N-Terminal ModificationsThe maturation of bacterial polypeptides begins cotranslationally as the polypeptide exits the ribosome. The first amino acid, N-formylmethionine (fMet), is typically modified at the...
547
Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
Some signaling systems generate...
8.0K